A research team led by Prof. ZHENG Mingyue from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences introduced a new deep learning method, SurfDock, which demonstrates good performance in both retrospective and prospective virtual screening tasks.
Dr. TIAN Ye's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, identified eight genera of bacterial isolates from Arabidopsis root bacterial isolates that could extend lifespan in C. elegans, and found that Mycobacterium sp. Root265 displayed the most pronounced extension effect.
Chinese scientists have developed a novel two-dimensional (2D) framework, the “Health State Map (HSM),” to define metabolic health and nutritional capacity. The study was published online in National Science Review.
A research team from the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences revealed that aging specifically impairs the generation of CD8+ tissue resident memory T cells (TRM) and thus compromises the antitumor defensive activity of aged CD8+ T cells.
A Chinese research team has recently traced the discovery of itaconate as an immune modulator and effector molecule, described the development of fluorescent probes for itaconate, and summarized recent research findings on the mechanisms of itaconate transport between cells in a review article published in Cell Insight on Nov. 22.
Researchers from the Shanghai Institute of Materia Medica and the Shanghai Institute of Nutrition and Health, utilizing artificial intelligence algorithms combined with pharmacological methods, predicted and confirmed that the stimulator of interferon genes is a key target of Ginkgetin, an active ingredients in Ginkgo biloba extract, for alleviating aging.
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