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metformin;cellular aging;GPx7;cell aging;Nrf2;aging

How Metformin Delays Human Cellular Aging[Apr 20, 2018]

Recently, the effects of metformin on elongating lifespan have been demonstrated in some animal models. The researchers at the Institute of Biophysics of Chinese Academy of Sciences reported that chronic low-dose metformin treatment upregulates the endoplasmic reticulum-localized glutathione peroxidase 7 (GPx7) and delays aging in human cells.

neuropeptide Y;NPY;anti-obesity;food intake;obesity;

Characterizing 'Keyhole' Is First Step to Fighting Obesity at Cellular Level[Apr 20, 2018]

An international team has uncovered the potential to beat obesity at the cellular level, characterizing for the first time a complex, little-understood receptor type that, when activated, shuts off hunger. Their findings are published online in Nature. The next step in this molecular-level research is target validation: proving that the receptor really does control hunger.

yttrium aluminum garnet;nanoceramics;LED;ceramics

New Strategy to Transparent Yttrium Aluminum Garnet-based Nanoceramics[Apr 20, 2018]

A research team led by Prof. LI Jianqiang from the Institute of Process Engineering proposed the innovative idea of using solidification-amorphous crystallization method to prepare YAG transparent ceramics. They used the containerless solidification technique to suppress the nucleation of the high undercooling state of the melt.

grain-boundary;solar cell;perovskite

Continuous Grain-Boundary Network Stabilizes High-Efficiency Solar Cells[Apr 20, 2018]

A research team led by Prof. PADTURE Nitin P. and Prof. ZHOU Yuanyuan from Brown University, USA as well as Prof. PANG Shuping from Qingdao Institute of Bioenergy and Bioprocess Technology demonstrated the continuous chemical functionalization of grain boundaries in perovskite thin films by using a tri-block copolymer that exhibits both hydrophilicity and hydrophobicity.

neuropeptide Y;NPY;anti-obesity;food intake;obesity;

Neuropeptide Y Y1 Receptor Structures Offer New Opportunities for Anti-obesity Drug Discovery[Apr 19, 2018]

Recently, scientists from the Shanghai Institute of Materia Medica of Chinese Academy of Sciences, and international collaborators, determined the high-resolution atomic structures of human Y1R bound to two structurally diverse antagonists UR-MK299 and BMS-193885. The finding provided insights into the pharmacology of NPY receptors and offered new opportunities for anti-obesity drug discovery.

carbon pool;terrestrial ecosystem;carbon;biomass

Researchers Update the Estimates of Carbon Pools in China's Terrestrial Ecosystems[Apr 19, 2018]

Research group led by Prof. FANG Jingyun from the Institute of Botany, has been studying the carbon pool/sink of China's terrestrial ecosystems for a long time. the group has conducted an intensive field campaign to investigate all sectors of carbon stocks in China's forests, shrublands, grasslands, and croplands, to better estimate the regional and national carbon pools and to explore the biogeographical patterns and potential drivers of these pools.

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