Researchers led by Prof. WU Qingfeng at the Institute of Genetics and Developmental Biology explored the ongoing process of neural cell competition, a fundamental mechanism that shapes the brain across the lifespan, providing fresh insights into how brain cells continuously "compete" for survival and how this competition impacts brain development, wiring, function, and aging.
A team led by FU Xiangdong and LU Fei from the Institute of Genetics and Developmental Biology has achieved a near-complete assembly of the wheat CS genome, addressing the issues of high repetitive sequences and polyploidy in wheat genomics and providing a model for sequencing other complex crop genomes.
Chinese scientists from Prof. ZHOU Jianmin’s team at the Institute of Genetics and Developmental Biology revealed that a widespread plant defense metabolite may help combat bacterial diseases in crops. The metabolite, erucamide, inhibits the virulence of pathogenic bacteria by specifically targeting the Type III Secretion injectisome assembly.
A research team led by TIAN Zhixi from the Institute of Genetics and Developmental Biology, in collaboration with colleagues, has pioneered a groundbreaking "macro-single-cell-spatial" three-level transcriptional analysis system.
A new study led by Profs. FAN Kelong and YAN Xiyun from the Institute of Biophysics introduces a novel ferritin-based delivery system for small interfering RNA targeting glioblastoma, a breakthrough that could enhance RNA interference therapies for cancer treatment.
Researchers from the Shanghai Institute of Materia Medica, the Sun Yat-sen University, and the Shanghai Institute of Immunity and Infection, using genome mining and enzymology techniques, discovered several coral terpene synthases and thoroughly elucidated the catalytic mechanism of a biflorane synthase, PcTS1.
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