A research team led by Prof. CAI Huaqing from the Institute of Biophysics has recently used the Dictyostelium model system and a proteomics-based approach to reveal the molecular mechanism of macropinosome formation controlled by Ras signaling.
Recently, a collaborative research team led by Prof. CHEN Chang from the Institute of Biophysics of the Chinese Academy of Sciences (CAS) and Prof. YAO Yonggang from the Kunming Institute of Zoology of CAS, showed that S-nitrosoglutathione reductase (GSNOR) regulates the S-nitrosation of protein kinase C-alpha (PKCα), affecting PKCα kinase activity, and thereby participating in morphine analgesic tolerance.
Researchers led by Prof. WANG Likun from the Institute of Biophysics have developed a novel fluorescence reporting system that allows researchers to visualize the accumulation of unfolded proteins within the ER lumen in living cells in real time.
Researchers from the Wuhan Botanical Garden analyzed the content, composition, distribution, and biosynthesis of B. striata (BSP), obtained candidate enzyme genes involved in BSP biosynthesis, and characterized the cellulose synthase-like family A gene family in the glucomannan polymerization of the cell wall and BSP.
A research team led by Eric H. Xu and ZHAO Lihua from the Shanghai Institute of Materia Medica, employing single-particle cryo-electron microscopy (cryo-EM) techniques, unveiled three-dimensional structures of SSTR5 in complex with the natural neuropeptide agonist cortistatin-17 (CST17) and clinically approved drug octreotide, thus shedding light on molecular mechanisms underlying SSTR5 activation by these ligands.
Researchers from the Wuhan Botanical Garden determined a new Callicarpa species and named it Callicarpa yongshunensis Wen B.Xu, Xiao D.Li & Yan L.Liu.
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