A research team from the Hangzhou Institute of Medicine of the Chinese Academy of Sciences resolved the first high-resolution structure of the sgc8c DNA aptamer that targets protein tyrosine kinase 7 (PTK7), engineered two optimal sgc8c variants for disease theranostics efficiently, and revealed new principles for the sophisticated structural and functional organization of DNA molecules.
The lab of Prof. George Fu Gao at the Institute of Microbiology of the Chinese Academy of Sciences revealed the spike (S) protein structures of the recently emerged BA.2.86, JN.1, EG.5, EG.5.1 and HV.1 variants of SARS-CoV-2, and conducted systematic comparative analysis on these sub-variants.
Dr. Raymond Chan from the Institute of Psychology, together with his collaborators, have designed a cross-sectional study to measure negative symptoms using second-generation scales in patients with treatment resistant schizophrenia.
A research team led by Prof. YE Keqiong from the Institute of Biophysics developed a high-throughput method consisting of RNA circularization, targeted amplification, and deep sequencing (CircTA-seq) to profile ribosomal RNA (rRNA) processing intermediates at single-molecule and single-nucleotide resolution.
Researchers at the Wuhan Botanical Garden conducted germination experiments with seeds from a species-rich alpine meadow in the Hengduan Mountains to find out whether and how the germination strategies of seeds with and without pericarps were influenced by maternal conditions and intrinsic resource levels.
Scientists from the Institute of Botany have identified Eocene, Oligocene, and Miocene boundaries as turning points for the transition of survival strategies in the grape family (Vitaceae).
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