/   Home   /   Newsroom   /   News Updates

Research Opens up Stem-cell Potential

Aug 12, 2019     Email"> PrintText Size

Shanghai scientists have made new discoveries about the development of cells in early embryos, paving the way for more efficient methods to obtain stem cells for certain human organs. This may in turn promote the development of stem cell-related regenerative medicine.

Stem cell-related therapies, including for diseases in the immune and nervous systems for which no drugs are available, offer prospective medical breakthroughs in the next one or two decades.

However, several factors, including little cell differentiation, a shortage of functional cells, as well as the immaturity and low purity of cells, hinder the technique's application. The unsolved mysteries surrounding stem cells in the early stages of life may be the root cause, experts said.

Stem cells in embryos can develop into an array of different cells, so their use may lead to new regenerative techniques.

The research - conducted by a group of scientists from the Shanghai Institute of Biochemistry and Cell Biology, CAS-MPG Partner Institute for Computational Biology and Guangzhou Institutes of Biomedicine and Health, all part of Chinese Academy of Sciences - established a molecular map for genes in mouse embryos, enabling the tracking of cell "ancestors" in different locations.

"We revealed the fine developmental trajectory of progenitor cells that have not been observed by a traditional approach," said Jing Naihe, a leading researcher on the team. For example, some cells previously believed to have derived separately may have common progenitors, Jing said.

A paper about the study was published on the website of the UK-based journal Nature on Thursday.

Such findings are a major revision and supplement to the theory of classical developmental biology established since the late 1980s, according to the institute.

"The findings may help scientists develop new methods to obtain stem cells for the liver, pancreas and spinal cord, and contribute to related disease research and stem cell-related regenerative medicine," he said.

Hui Lijian, a researcher with the Shanghai Institute of Biochemistry and Cell Biology, said that the research may also shed light on the study and understanding of the development of some diseases in adulthood. (China Daily)

(Editor: CHEN Na)

Contact

Phone:
E-mail:

Related Articles

stem cell;stem cell research

Mini-program of Stem Cell Research Starts Trial Operation

Apr 30, 2019

China has launched a smart mini-program of stem cells research to facilitate data and information services, according to Chinese Academy of Sciences (CAS). The WeChat mini-program, called stem cell research assistant, was jointly developed by the Cheng...

stem cell;stem cell clinic research program;retinal pigment degeneration;ovarian dysfunction;intrauterine adhesions

China Launches New Stem Cell Clinic Programs

Mar 18, 2019

The Chinese Academy of Sciences (CAS) on Sunday announced the launches of three stem cell clinic research programs to treat severe eye and gynecological diseases. The three registered programs will focus on treating retinal pigment degeneration, ovaria...

stem cell;bioscience

Stem Cell R&D Center Opens in East China

Jun 26, 2018

A research and development (R&D) base for stem cells storage and application recently went into operation in Nanjing, capital of east China's Jiangsu Province. The base can preserve three million oral stem cells and umbilical cord stem cells. It is exp...

Contact Us

Copyright © 2002 - Chinese Academy of Sciences