Researchers from the Center for Excellence in Molecular Cell Science (Shanghai Institute of Biochemistry and Cell Biology) and Tongji University identified a fibrous-layer resident subpopulation of P-SSCs labeled by Angptl7. They found that these cells are crucial for bone fracture repair by mediating endochondral ossification, but exhibit minimal osteogenic capacity during postnatal bone development and maintenance.
A new study demonstrates that rapid, label-free readings from individual yeast cells can be translated into many of these same key process metrics—while also uncovering cell-to-cell variation masked by bulk testing methods.
Dr. DONG Peng's team from the Shenzhen Institute of Advanced Technology and the collaborators from Sun Yat-sen University discovered that TMZ treatment induces the formation of HDAC1-CTCF condensates in GBM cells, and they identified the small-molecule compound Resminostat as a therapeutic agent capable of targeting these condensates.
Led by Prof. ZHAO Ruilin from the Institute of Microbiology of the Chinese Academy of Sciences, researchers showed how climate dynamics and a key gene for adaptive evolution and domestication jointly shaped the button mushroom's diversity.
Scientists have elucidated how NodD recognizes flavonoids by resolving, for the first time, the high-resolution crystal structure of the complex formed between the NodD protein of pea rhizobia and the flavonoid compound hesperetin. Through this process, the researchers identified key structural elements in NodD that determine signal specificity.
A recent study led by Prof. ZHANG Xiaoming's team at the Institute of Zoology of the Chinese Academy of Sciences (CAS), in collaboration with Prof. Ian T. Baldwin's group at the CAS Center for Excellence in Molecular Plant Sciences, has uncovered a novel ecological strategy. Rather than passively "hitchhiking" within insect vectors, rice viruses actively manipulate plant defense pathways to protect their insect carriers.
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