The Chinese Academy of Sciences (CAS) has launched an emergency project for diagnosis, prevention and treatment of serious acute respiratory syndrome (SARS), the spread of which has grown to crisis proportion in parts of China and many other countries in the world. This joint project involves the CAS Beijing Genomics Institute, the CAS Wuhan Institute of Virology, the CAS Institute of Microbiology, and the CAS Shanghai Institutes for Biological Sciences. It is being undertaken through cooperation with the Institute of Microbiology & Epidemiology of the Academy of Military Medical Sciences and the Chinese Center for Disease Control and Prevention.
The project is designed, among others, to obtain the exact sequence of the SARS viruses, discover the characteristics of their variations, and analyze the characteristics of such variations at the genome level. Scientists participating in the project will also pinpoint the sources of the SARS viruses and track down the course of their spread. They are expected to eventually develop vaccines for SARS prevention and ensure trial production of the deactivation and genetically engineered vaccines.
The project calls for the sequencing of whole genome of SARS viruses and study of their variations, pathogenic study of the viruses, and identification of the epidemic animals for SARS, in particular suspected animals such as birds, pigs, cattle, monkeys and rats. Also called for are development and preparation of SARS coronavirus vaccines, as well as SARS-related pathogenic and immunological studies.
CAS notes that interdisciplinary, time-consuming efforts are need to conquer the deadly SARS epidemic. At present, CAS scientists are concentrating on the diagnosis, prevention and treatment of the disease. They are sparing no effort to ensure that their research results will be put to clinical application and industrial production within the shortest possible time.
CAS hopes that the relevant departments under the central government will, through coordination, help meet the following needs:
First is samples taken from patients who are different in age and symptoms and in different stages of the disease, including tissues of lesion, blood and wiped samples of the respiratory system, nose and throat. Supply of virus samples must also be ensured. CAS requests the Ministry of Health and the Beijing Municipal Government to streamline the procedures of approval for the use and distribution of the tests to be developed. Other aspects of the work should also be well coordinated and streamlined, including for example training of the needed personnel and feedback of information on clinical application of the research results.