Chinese Scientists Find Nudel and Cytoplasmic Dynein Significant in Spindle Matrix Assembly
Two Chinese scientists published their research finding about Nudel and cytoplasmic dynein in the British science journal Nature Cell Biology on February 9, marking a new achievement in China's cell biology study.
Nudel and cytoplasmic dynein play significant roles in the assembly of spindle matrix, and in regulating proper formation of spindles in mitosis process, according to the research, which was carried out by Zhu Xueliang, a researcher of Shanghai Institute for Biological Science, Chinese Academy of Sciences, and Zheng Yixian, professor with Carnegie Institution of Washington.
Spindles, a spindle-like dynamic structure formed by canaliculus, see to equational separation of genetic material (chromosome) in mitosis process of eucaryotic cell. Therefore, abnormity of spindles will cause genetic instability and lead to the death of cells or result in tumors and cancers.
The research was jointly sponsored by China's Ministry of Science and Technology, National Natural Science Foundation of China, Chinese Academy of Sciences, Howard Hughes Medical Institute and Carnegie Institution of Washington in the United States.
Abstract Links: http://www.nature.com/ncb/journal/vaop/ncurrent/abs/ncb1832.html
Homepage of Zhu Xueliang: http://www.sibcb.ac.cn/PI.asp?id=4
Homepage of Zheng Yixian: http://www.hhmi.org/research/investigators/zheng_bio.html
