Phononic Crystal Based Acoustic Sieve for Tunable Manipulations of Particles by Highly Localized Radiation Force
Jun 24, 2014 Email"> PrintText Size
The ability to sort, sieve, and manipulate micro- and nano-scale particles, especially in a tunable manner, is highly desirable for various applications ranging from targeting drug delivery to additive manufacturing. A conventional sieve uses a mesh of fixed size for separating smaller particles from the particle mixture of various sizes, but it cannot sort out different materials of same size and is incapable of particle manipulation. Optical and acoustic tweezers have been developed to trap and manipulate nanoparticles, biomolecules, and organisms, yet they can only capture few particles at a time and are difficult to scale up.
Researchers of Shenzhen Institutes of Advanced Technology (SIAT) introduce the concept of acoustic sieve, which is based on the highly localized periodic radiation force induced by the resonance transmission of acoustic wave across a phononic crystal plate. The acoustic sieve is capable of trapping, aligning, sorting and transferring a large number of particles according to their sizes or densities, all in a tunable and scalable manner. Different from conventional standing wave technique, this work represents a significant advance and methodological leap forward in acoustic manipulation of microscopic particles which may find broad applications in new additive material fabrications and cell sorting in bioenengineering.
The research results have been published onlineon June 11 in Physical Review Applied, and labelled by “Editor’s Suggestion” and “Featured in Physics” as highlights. This research received grants from National Natural Science Foundation of China and 973 Research Program of China, and was also supported by Beijing Center for Mathematics and Information Interdisciplinary Sciences and Shenzhen Key Lab for Molecular Imaging.
The research group, led by Prof. ZHENG Hairong in SIAT- Paul C. Lauterbur Research Center for Biomedical Imaging, focus on ultrasonics, ultrasonic imaging-drugdelivery-therapy, acoustic manipulation and multimodality medical imaging.
Contact:
ZHENG Hairong, Ph. D.
Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences,
Shenzhen, China.
Tel: +86-0755-86392244, E-mail: hr.zheng@siat.ac.cn
Link to Full Text: http://journals.aps.org/prapplied/abstract/10.1103/PhysRevApplied.1.051001
Acoustic Sieveillustration (Image by SIAT)
The ability to sort, sieve, and manipulate micro- and nano-scale particles, especially in a tunable manner, is highly desirable for various applications ranging from targeting drug delivery to additive manufacturing. A conventional sieve uses a mesh of fixed size for separating smaller particles from the particle mixture of various sizes, but it cannot sort out different materials of same size and is incapable of particle manipulation. Optical and acoustic tweezers have been developed to trap and manipulate nanoparticles, biomolecules, and organisms, yet they can only capture few particles at a time and are difficult to scale up.
Researchers of Shenzhen Institutes of Advanced Technology (SIAT) introduce the concept of acoustic sieve, which is based on the highly localized periodic radiation force induced by the resonance transmission of acoustic wave across a phononic crystal plate. The acoustic sieve is capable of trapping, aligning, sorting and transferring a large number of particles according to their sizes or densities, all in a tunable and scalable manner. Different from conventional standing wave technique, this work represents a significant advance and methodological leap forward in acoustic manipulation of microscopic particles which may find broad applications in new additive material fabrications and cell sorting in bioenengineering.
The research results have been published onlineon June 11 in Physical Review Applied, and labelled by “Editor’s Suggestion” and “Featured in Physics” as highlights. This research received grants from National Natural Science Foundation of China and 973 Research Program of China, and was also supported by Beijing Center for Mathematics and Information Interdisciplinary Sciences and Shenzhen Key Lab for Molecular Imaging.
The research group, led by Prof. ZHENG Hairong in SIAT- Paul C. Lauterbur Research Center for Biomedical Imaging, focus on ultrasonics, ultrasonic imaging-drugdelivery-therapy, acoustic manipulation and multimodality medical imaging.
Contact:
ZHENG Hairong, Ph. D.
Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences,
Shenzhen, China.
Tel: +86-0755-86392244, E-mail: hr.zheng@siat.ac.cn
Link to Full Text: http://journals.aps.org/prapplied/abstract/10.1103/PhysRevApplied.1.051001
Acoustic Sieveillustration (Image by SIAT)
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