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No.4, 2022

	Contents
	194 In This Issue
	199 InBrief
	201 Looking into the Sun – Kuafu-1 in its first stride
	204 Top 10 Science Advances of 2022 in the News - Chinese Academicians' Picks
	213 Colossal Atomic-hydrogen Cloud Detected by FAST Hints at Early Interactions between Galaxies in Stephan's Quintet
	217 Scientific Expedition to the Earth Summit – A Closer Look at the Atmospheric and Glacial Marvels of Mount Qomolangma
	220 Harmonizing Timekeepers over Long-Distance with Ultra-Precision
	221 Scientists Capture the Image of Charge Transfer in Photocatalyst Particles
	223 Researchers Develop World's Largest Silicon Carbide Aspheric Mirror for Telescope Applications
	225 Ultra-Slow Hygroscopic Motion of Pine Cone Inspires New Soft Actuators
	226 Structural Insights into Folate Transporter May Offer Clues for Anticancer Drugs
	228 Endogenous Retrovirus Activation in Pupal Fruit Flies May Boost Adult Antiviral Defenses
	230 Unlocking Gene Networks Behind Magnetosome Formation in Magnetotactic Bacteria
	232 Unlocking the Secrets of Chitin Biosynthesis
	234 First Data Release from GECAM Mission
	236 First Results from LHAASO's Dark Matter Search Place Tighter Constraints on Dark Matter's Lifetime
	238 Nanoglues Stabilize Metal Atoms for Catalysis
	240 Advances in Li-rich Mn-based Layered Cathode Materials Enable High-performance Li-ion Batteries
	242 Rationalized Deep Learning Super-resolution Microscopy Enables Live Imaging of Rapid Subcellular Events
	245 Successful Hypothermia in Nonhuman Primate Paves the Way for Future Application in Human Torpor
	247 New Strategy for Targeted Degradation of Proteins
	248 Scientists Reveal Protein Mechanism Behind TB Pathogen Success
	250 Ancient "Shark" from China Is Humans' Oldest Jawed Ancestor: Palaeontologists discover a 439-million-year-old "shark" that forces us to rethink the timeline of vertebrate evolution
	253 Fish Fossils Breathe New Life into Fin and Limb Evolutionary Hypothesis
	255 Rare Fossil Teeth from China Overturn Long-held Views about Evolution of Vertebrates