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β-carotene;Y.lipolytica;biosynthesis

Oleaginous Yeast Serves as β-carotene Cell Factory[Apr 20, 2017]

Prof. YANG Sheng and colleagues at Shanghai Institute of Plant Physiology and Ecology of Chinese Academy of Sciences developed a series of genome editing tools for Y. lipolytica. And they generated an efficient biosynthetic pathway using strong promoters and multiple gene copies for each of the 12 steps.

single-particle tracking;human immunodeficiency virus;HIV;macrophage;virus;HIV-1-QDs;quantum dot;QD

Single-particle Tracking Reveals Mechanism for HIV-1 Productive Entry into Primary Macrophages[Apr 18, 2017]

Prof. CUI Zongqiang from Wuhan Institute of Virology of the Chinese Academy of Sciences, Prof. ZHANG Xian'en from Institute of Biophysics of the Chinese Academy of Sciences, and Prof. WU Yuntao from George Mason University have constructed a quantum dot (QD)-encapsulated infectious HIV-1 particle to observe the viral entry pathway to the macrophages at a single-particle level in live cells.

remote sensing;image classification

Supervised Multi-View Canonical Correlation Analysis Ensemble Helps Realize Heterogeneous Domain Adaptation in Remote Sensing Image Classification[Apr 19, 2017]

A team of scientists from the Xinjiang Institute of Ecology and Geography led by Jilili Abuduwaili present novel techniques designed to address heterogeneous domain adaptation problems, i.e., situations in which the data to be processed and recognized are collected from different heterogeneous domains.

intestine;immune homeostasis;Bap180;Drosophila

Scientists Reveal A Conserved Mechanism of Intestinal Innate Immune Homeostasis[Apr 19, 2017]

Professor PAN Lei at the Institute of Biophysics (IBP) of the Chinese Academy of Sciences and other colleagues found that flies deficient of intestinal Bap180 (Baf180 in mammals), a subunit of chromatin remodeling SWI/SNF complex, succumbed to excessive inflammation rather than bacterial overload after bacterial infection.

CRISPR;FnCpf1;LbCpf1;gene editing

A New Class 2 CRISPR System Helps to Realize Multiplex Gene Editing in Rice[Apr 19, 2017]

Cpf1 is a dual nuclease that not only cleaves target DNA but also processes its own CRISPR RNA. A study led by Prof. ZHU Jiankang's lab at Institute of Plant Physiology and Ecology of Chinese Academy of Sciences tested FnCpf1 and LbCpf1 for single and multiplex gene editing in rice.

irrigation;WRF;regional climate

IAP Scientists Unravel Climatic Effect of Irrigation over the Yellow River Basin[Apr 19, 2017]

In the current study, CHEN and his team developed a new irrigation scheme based on the Noah land surface model, and then coupled it with the Weather Research and Forecasting regional climate model.

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