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TGFβ;SMAD7;EMT;epithelial-mesenchymal transition;cancer cell

MicroRNA-182 Targets SMAD7 to Potentiate TGFβ-Induced Epithelial-Mesenchymal Transition and Metastasis of Cancer Cells[Dec 23, 2016]

Researchers from the Institute of Health Sciences, Shanghai Institutes for Biological Sciences of Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine found that in cancer cells the SMAD7-mediated TGFβ negative feedback loop is disrupted by microRNA-182 (miR-182), which potentiates TGFβ-induced EMT and metastasis microenvironment adaptation.

ZIKV;Zika virus;infectious disease

Molecular Determinants of Human Neutralizing Antibodies Isolated from a Zika Patient[Dec 16, 2016]

Zika virus (ZIKV) is a flavivirus that is currently causing global concern. Research groups of Prof. YAN Jinghua from the Key Laboratory of Microbial Physiological and Metabolic Engineering and George Fu Gao from Key Laboratory of Pathogenic Microbiology and Immunology at the Institute of Microbiology of Chinese Academy of Sciences described the isolation of Zika-specific human neutralizing antibodies with high potency from a convalescent Zika patient and characterization of these antibodies through in vitro neutralization assays, mechanism of binding through structural studies, and in vivo protection in a mouse model.

Dolomitization;Carbonate Reservoir;Porosity;Cambrian

Researchers Uncover the Dolomitization Mechanisms of Camrbian Petroleum Reservoirs[Dec 22, 2016]

Associate Prof. JIANG Lei and his colleagues from Institute of Geology and Geophysics of the Chinese Academy of Sciences, found that five stages of dolomitization were responsible for the formation of various types of dolomite in the deeply buried Cambrian unit in the Tarim Basin, northwest China. They further related the different dolomitization events to the origin of various types of pore space in these reservoirs. This work was published in Sedimentology. Dolomite samples were collected from well cores across the whole basin, and from several outcrops at the northwestern edge of the basin.

sunspot;solar flare;rotation;counter-clockwise rotation;solar interior;

When Does a Sunspot's Rotation Completely Reverse?[Dec 22, 2016]

BI Yi and Prof. JIANG Yunchun from Yunnan Observatories of the Chinese Academy of Sciences, for the first time reported that the direction of a sunspot's rotation is reversed impulsively, based on observations from the Helioseismic and Magnetic Imager. They noted that the sunspot rotated counter-clockwise before an X1.6 flare but clockwise during it. The counter-clockwise rotation in the sunspot before the flare did play a role in transporting the negative helicity from the solar interior into the solar corona.

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