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Research Progress

New Approach Acquired for DNA Separation and Detection

Dec 29, 2010

Separation applications are very important in the field of chemistry and chemical engineering. At the present time, the development of a facile, economical and simple strategy to synthesize a new monodisperse, easily-modified substitute for magnetic nanoparticles with controlled size is a great challenge and important research topic.  

In their recent published article, YANG Xuan and other CIAC (Chang Chun Institute Of Applied Chemistry, Chinese Academy Of Sciences) researchers report a rapid, low-cost, high-yield and simple strategy to synthesize highly crystalline silver micro-dendrites (SMDs) whose surface is very clean with no surfactant on it and it is very easy to modify different molecules on the surface according to various needs. Hydroxylamine is used as the reducing agent in this route and the final products are nitrogen and water, importing no other chemical agents. Moreover, the research group uses this kind of SMDs for DNA separation and detection merely by earth gravity instead of magnetic force of electric or magnetic field.

The research is supported by the National Natural Science Foundation of China (20735003, 20890020) and National Program on Key Basic Research Project of China (973 Progam 2009CB930100, 2010CB933600). The article has been published in Chem. Commun., 2010, 46, 8818-8820.

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