Asian Journal of Andrology (AJA) published an original paper on a novel genetic mutation of prostate cancer in black people. The research was then reported by more than 30 news agencies including Science News.
The original article is entitled “Identification of a novel germline missense mutation of the androgen receptor in African American men with familial prostate cancer”. In this paper, Professor Shahriar Koochekpour and his colleagues at Louisiana State University identified a germline AR-A1675T substitution mutation in the DNA-binding domain in three affected members of an African-American family with a history of early-onset prostate cancer.
This finding may represent a potential genetic biomarker for predisposition to familial prostate cancer in African-American men. The results of this study combined with future large-scale genome-wide association or expression array analyses may determine the genetic profiles that confer population-attributable disease risk or aggressiveness for prostate cancer.
Right after the release of this novel finding at the Nature News Wire, it aroused global attention and intense discussion. HealthDay News, a worldwide health media, firstly highlighted this report and forecasted that the finding may explain higher incidence among blacks than whites. Immediately, more than 30 global Health Information networks reproduced this report, such as Science News, Summit Health Group News, Meriter Health Services News, NIH MedlinePlus, Rocket News, HealthScout News, Health News U.S., and BusinessWeek.
Asian Journal of Andrology, the official journal of Asian Society of Andrology, is sponsored by the Shanghai Institute of Materia Medica, Chinese Academy of Sciences. It was started in June 1999 and is a quarterly published in English.
Full text of the research paper: http://www.nature.com/aja/journal/vaop/ncurrent/full/aja20105a.html.
Link to the journal: http://www.asiaandro.com/index.asp
